We report here a draft genome assembly of strain 4866-2_S43 isolated from a eucalyptus lesion in Argentina and what until recently was caused by Xanthomonas axonopodis pv. eucalyptorum (Xae). The genome size is 5,188,607 bp, with a G+C content of 64.66%. Comparative analysis reveals that the closest relative of strain 4866-2_S43 is Xae LPF 602, isolated in Brazil. Comparison of the whole genome sequences revealed an average nucleotide identity (ANI) of 99.96%. between the two strains. ANIs were determined between the whole genome sequence of strain 4866-2_S43 and the genomes of all currently validated Xanthomonas spp. These results revealed that strain 4866-2_S43 had greater than 95% with X. citri pv. citri,and X. citri pv. phaseoli, and less than 95% with X. euvesicatoria pv. alfalfae, X. perforans, and X. euvesicatoria pathovars euvesicatoria and eucalyptii.
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