Adrenocorticotropic hormone-independent Cushing's syndrome (CS) secondary to cortisol-secreting adrenal cortical carcinoma (ACC) in children has been seldom reported. We report on a 6-year-old girl diagnosed with CS due to a right-sided ACC. She presented with rapid onset obesity, virilization, and hypertensive urgency. Postserial diagnostic evaluation, control of hypertension, right adrenalectomy with en bloc resection of tumor mass were performed. The child had an excellent clinical and biochemical recovery with significant weight loss and return to normal serum cortisol levels.
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Patil et al. (2024) studied this question.
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