Mp49-06 Prostate Specific Antigen Screening Amongst Smokers: A U.S. National Behavioral Analysis

You have accessJournal of UrologyProstate Cancer: Detection & Screening IV (MP49)1 May 2024MP49-06 PROSTATE SPECIFIC ANTIGEN SCREENING AMONGST SMOKERS: A U.S. NATIONAL BEHAVIORAL ANALYSIS Ian Mitchell Harmatz, Khalid Y. Alkhatib, Morgan Leff, Brian D. Cortese, Nathaniel McLaughlan, Daniel S. Roberson, Katharine F. Michel, Benjamin Schurhamer, Daniel J. Lee, Stanley Bruce Malkowicz, Trinity J. Bivalacqua, Thomas Guzzo, and Phillip M. Pierorazio Ian Mitchell HarmatzIan Mitchell Harmatz , Khalid Y. AlkhatibKhalid Y. Alkhatib , Morgan LeffMorgan Leff , Brian D. CorteseBrian D. Cortese , Nathaniel McLaughlanNathaniel McLaughlan , Daniel S. RobersonDaniel S. Roberson , Katharine F. MichelKatharine F. Michel , Benjamin SchurhamerBenjamin Schurhamer , Daniel J. LeeDaniel J. Lee , Stanley Bruce MalkowiczStanley Bruce Malkowicz , Trinity J. BivalacquaTrinity J. Bivalacqua , Thomas GuzzoThomas Guzzo , and Phillip M. PierorazioPhillip M. Pierorazio View All Author Informationhttps://doi.org/10.1097/01.JU.0001008696.31772.28.06AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Smoking is associated with higher-grade prostate cancer (PCa) at diagnosis and increased overall and PCa-specific mortality. A possible explanation for these findings is lower uptake of prostate specific antigen (PSA) screening amongst smokers. Previous studies indicate smokers are less likely to adhere to recommended PSA screening. We investigate the association between smoking and PSA screening using the CDC Behavioral Risk Factor Surveillance System (BRFSS) survey to provide a nationally representative model. We hypothesize that smokers are less likely to undergo recommended PSA screening. METHODS: We analyzed men aged 55-69 who responded to the cigarette smoking and PSA screening questions of the 2018 BRFSS. PSA screening prevalence was calculated for each group. Complex weighted multivariable Poisson regression modeling adjusted for age, race, marriage status, education, income, health insurance, and use of a personal doctor was used to calculate the adjusted relative risk of undergoing PSA screening. RESULTS: We analyzed 58,996 individuals representing a national estimate of 27.04 million. The national prevalence of PSA screening was 39% [95% CI; 39-40%]. The prevalence of PSA screening was 42% [95% CI; 41-44%] for never smokers, 27% [95% CI; 25-29%] for current smokers, and 42% [95% CI; 39-40%] for former smokers (Table 1). Among current smokers, PSA screening prevalence was 27% [95% CI; 24-29%] daily smokers and 29% [95% CI; 24-33%] for non-daily smokers. The adjusted relative risk for undergoing PSA screening in comparison to never smokers was 0.81 for current smokers (95% CI: 0.75-0.88, p<0.01) and 0.99 for former smokers (95% CI: 0.94-1.03, p=0.53) (Table 2). CONCLUSIONS: Smokers are significantly less likely to undergo PSA screening. Resultant delays in diagnosis may contribute to worse PCa detection and outcomes in smokers. Interventions to increase screening in this population may be particularly effective in improving PCa outcomes. Further studies are needed to develop strategies to address reduced PSA screening rates in smokers. Source of Funding: N/A © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e784 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Ian Mitchell Harmatz More articles by this author Khalid Y. Alkhatib More articles by this author Morgan Leff More articles by this author Brian D. Cortese More articles by this author Nathaniel McLaughlan More articles by this author Daniel S. Roberson More articles by this author Katharine F. Michel More articles by this author Benjamin Schurhamer More articles by this author Daniel J. Lee More articles by this author Stanley Bruce Malkowicz More articles by this author Trinity J. Bivalacqua More articles by this author Thomas Guzzo More articles by this author Phillip M. Pierorazio More articles by this author Expand All Advertisement PDF downloadLoading ...