MP55-08 OBESITY IN PEDIATRIC KIDNEY TRANSPLANT PATIENTS IS NOT ASSOCIATED WITH HIGHER RISK OF POSTOPERATIVE COMPLICATIONS—a 10-YEAR SINGLE CENTER EXPERIENCE

You have accessJournal of UrologyPediatrics IV (MP55)1 May 2024MP55-08 OBESITY IN PEDIATRIC KIDNEY TRANSPLANT PATIENTS IS NOT ASSOCIATED WITH HIGHER RISK OF POSTOPERATIVE COMPLICATIONS—a 10-YEAR SINGLE CENTER EXPERIENCE Franziska Juliane Richter, Fabian Doktor, Mandy Rickard, Priyank Yadav, Michael E. Chua, Joana Dos Santos, Chia Wei Teoh, Jin K. Kim, and Armando J. Lorenzo Franziska Juliane RichterFranziska Juliane Richter , Fabian DoktorFabian Doktor , Mandy RickardMandy Rickard , Priyank YadavPriyank Yadav , Michael E. ChuaMichael E. Chua , Joana Dos SantosJoana Dos Santos , Chia Wei TeohChia Wei Teoh , Jin K. KimJin K. Kim , and Armando J. LorenzoArmando J. Lorenzo View All Author Informationhttps://doi.org/10.1097/01.JU.0001008616.01808.0f.08AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Obesity may be considered a contraindication to pediatric kidney transplantation due to suboptimal outcomes. Herein we aimed to determine if pediatric patients with elevated body-mass index (BMI) (>85th percentile) are at higher risk for short-term complications. METHODS: After review of our transplant database (2010-2020), patients>2 – 18 years were assigned to groups based on BMI percentiles at the time of surgery: A (normal; 5th-85th percentile; n=120) and B (obesity and overweight; >85th percentile; n=60). Patients underwent a 1 to 2 ratio nearest-neighbor matching with propensity score based multivariable logistic regression model adjusting for age, sex and underlying diagnosis. RESULTS: Of 180 included patients, group B underwent transplantation significantly earlier in life (p=0.0041) than group A (66.5 months; IQR25,221 vs. 130.0 months; IQR24,209), with lower creatinine levels at 3 and 6 months as well as 1 year postoperatively. There was no difference in OR times, warm ischemia time, time to nadir creatinine, severity of and time to complications (p>0.05). However, more patients in group B required intraoperative blood transfusions (p=0.0063) with comparable blood loss and stayed longer at the hospital (LOS, p=0.0149, Table 1). CONCLUSIONS: The results of this study confirm that obesity in pediatric kidney transplant patients does not lead to higher likelihood of postoperative complications or worse graft function on early postoperative monitoring. Findings related to increased use of blood products and longer hospital stay deserve further evaluation. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e919 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Franziska Juliane Richter More articles by this author Fabian Doktor More articles by this author Mandy Rickard More articles by this author Priyank Yadav More articles by this author Michael E. Chua More articles by this author Joana Dos Santos More articles by this author Chia Wei Teoh More articles by this author Jin K. Kim More articles by this author Armando J. Lorenzo More articles by this author Expand All Advertisement PDF downloadLoading ...