Pd06-09 Augmentation Cystoplasty Negatively Impacts Early Renal Outcomes in Pediatric Renal Transplant Recipients

You have accessJournal of UrologyTransplantation & Vascular Surgery I (PD06)1 May 2024PD06-09 AUGMENTATION CYSTOPLASTY NEGATIVELY IMPACTS EARLY RENAL OUTCOMES IN PEDIATRIC RENAL TRANSPLANT RECIPIENTS Priyank Yadav, Dheidan Alshammari, Adree Khondker, Jin Kyu Kim, Michael E Chua, Mandy Rickard, and Armando Lorenzo Priyank YadavPriyank Yadav , Dheidan AlshammariDheidan Alshammari , Adree KhondkerAdree Khondker , Jin Kyu KimJin Kyu Kim , Michael E ChuaMichael E Chua , Mandy RickardMandy Rickard , and Armando LorenzoArmando Lorenzo View All Author Informationhttps://doi.org/10.1097/01.JU.0001008592.06852.43.09AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Pediatric renal transplant recipients may require prior bladder augmentation due to congenital or acquired bladder anomalies. However, the impact of augmentation cystoplasty on the allograft remains unexplored. The objective of this study was to compare early renal outcomes in pediatric renal transplant recipients with and without augmentation cystoplasty. METHODS: Data of patients who were performing clean intermittent catheterization and subsequently underwent renal transplantation between 2000 and 2021 was retrieved. The patients were broadly divided into group 1 (augmentation cystoplasty) and group 2 (no augmentation cystoplasty). Baseline characteristics, intraoperative outcomes and postoperative outcomes were compared between the two groups. Renal function was estimated by calculating the glomerular filtration rate (GFR) based on serum creatinine during follow up at 3 months and 1 year after transplant. Categorical variables were compared using Chi-squared and Fisher exact test and continuous variables were compared using T-test. RESULTS: Group 1 consisted of 23 patients and group 2 consisted of 30 patients. Age at transplantation, gender distribution, incidence, type and duration of dialysis, BMI and type of allograft (living donor vs. cadaveric) did not differ significantly between the two groups (Table 1). Mean pre-operative urine output was greater in group 2 (p=0.005). Although estimated blood loss, hospital stay and ICU stay were greater in group 1, the difference was not statistically significant (Table 2). Group 1 was associated with a higher incidence of progression to chronic kidney disease (CKD) (GFR<60 mL/min) compared to group 2 at both 3 months (p=0.031) and 1 year (p=0.041). The incidence of complications (like lymphocele, rejection, infection, hematoma, urine leak) did not differ significantly between the two groups. CONCLUSIONS: Augmentation cystoplasty in pediatric renal transplant recipients is associated with inferior early renal outcomes compared to those without augmentation. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e164 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Priyank Yadav More articles by this author Dheidan Alshammari More articles by this author Adree Khondker More articles by this author Jin Kyu Kim More articles by this author Michael E Chua More articles by this author Mandy Rickard More articles by this author Armando Lorenzo More articles by this author Expand All Advertisement PDF downloadLoading ...