PD28-09 A POPULATION ANALYSIS OF DELAYED EJACULATION USING a CLAIMS DATABASE: CHARACTERISTICS AND NATIONAL TRENDS IN PREVALENCE, INCIDENCE, AND PHARMACOTHERAPY

You have accessJournal of UrologySexual Function/Dysfunction: Evaluation I (PD28)1 May 2024PD28-09 A POPULATION ANALYSIS OF DELAYED EJACULATION USING a CLAIMS DATABASE: CHARACTERISTICS AND NATIONAL TRENDS IN PREVALENCE, INCIDENCE, AND PHARMACOTHERAPY Brian Liao, Corey Able, Steven Banner, Clemens An, Joseph Sonstein, Laith Alzweri, and Taylor Kohn Brian LiaoBrian Liao , Corey AbleCorey Able , Steven BannerSteven Banner , Clemens AnClemens An , Joseph SonsteinJoseph Sonstein , Laith AlzweriLaith Alzweri , and Taylor KohnTaylor Kohn View All Author Informationhttps://doi.org/10.1097/01.JU.0001009380.44020.d3.09AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Delayed ejaculation (DE) is a sexual function disorder affecting up to 5% of men. The lack of a standardized definition contributes to ambiguity surrounding its prevalence and treatment patterns. Our primary objective is to comprehensively evaluate the trends in DE prevalence, incidence, treatments, and the medications and comorbidities associated with its diagnosis. METHODS: We utilized the TriNetX Diamond database to identify all adult males assessed between January 2013 and December 2019. To determine prevalence and incidence, we compared the number of men diagnosed with DE and those newly diagnosed with DE to the total number of men evaluated and those without a prior DE diagnosis, respectively, in six-month intervals. We assessed trend with Cochrane-Armitage tests, with significance set at an alpha level<0.05. We calculated pharmacotherapy rates by comparing the number of men prescribed each medication to the total number of men with DE in one-year intervals. RESULTS: We identified 23,164 adult men with a DE diagnosis. In the most recent period, 2,747 (0.02%) received a DE diagnosis and 1,375 (0.01%) were newly diagnosed. The Cochrane-Armitage test showed a significantly increasing trend in prevalence (trend=0.0005%, χ2=753.8, p-value=<0.0001) and incidence (trend=0.0001%, χ2=114.5, p-value = <0.0001). There has been a consistent rise in the proportion of men prescribed any medication since 2013. Testosterone was the most commonly prescribed, with 8.5% receiving a prescription with 3 years of diagnosis. Selective serotonin reuptake inhibitors (12.0%) were the most common medications at time of DE diagnosis. Figures 1 and 2 illustrate the temporal trends in prevalence/incidence and prescriptions over time, respectively. CONCLUSIONS: Delayed ejaculation has a low rate of clinical diagnosis but increasing prevalence. Rates of pharmacotherapy remain low. Further work is needed to investigate first line medical therapy if behavioral modification and psychotherapy fail. Download PPTDownload PPT Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e615 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Brian Liao More articles by this author Corey Able More articles by this author Steven Banner More articles by this author Clemens An More articles by this author Joseph Sonstein More articles by this author Laith Alzweri More articles by this author Taylor Kohn More articles by this author Expand All Advertisement PDF downloadLoading ...