Pd28-10 an International Prospective Registry of People With Postorgasmic Illness Syndrome

You have accessJournal of UrologySexual Function/Dysfunction: Evaluation I (PD28)1 May 2024PD28-10 AN INTERNATIONAL PROSPECTIVE REGISTRY OF PEOPLE WITH POSTORGASMIC ILLNESS SYNDROME Olivia Paulsen, Ifeoma Ikedionwu, Jasmin Banton, John Sun, Isaac Bronson, Omer Raheem, Amy M. Pearlman, Mesut Berkan Duran, Ege Can Serefoglu, and Rachel Rubin Olivia PaulsenOlivia Paulsen , Ifeoma IkedionwuIfeoma Ikedionwu , Jasmin BantonJasmin Banton , John SunJohn Sun , Isaac BronsonIsaac Bronson , Omer RaheemOmer Raheem , Amy M. PearlmanAmy M. Pearlman , Mesut Berkan DuranMesut Berkan Duran , Ege Can SerefogluEge Can Serefoglu , and Rachel RubinRachel Rubin View All Author Informationhttps://doi.org/10.1097/01.JU.0001009380.44020.d3.10AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Postorgasmic Illness Syndrome (POIS) describes a debilitating collection of flu-like or allergy-like symptoms experienced post-orgasm. The disorder can be divided into primary or secondary subtypes, and even further into seven clusters. POIS is considered a rare condition that is not well understood and poorly researched. This survey aims to create a registry of detailed information about individuals' experience with POIS, including symptomology, chronicity, and treatments trialed. METHODS: An IRB-approved RedCAP survey was created by the University of Chicago in September of 2023. The anonymous survey was distributed to the following online platforms: Twitter, Instagram, Reddit (r/POIS and r/SampleSize), and the POISCenter forum. The survey was closed on November 5th, 2023 and descriptive statistics were performed. RESULTS: 424 records were collected, with 94% reportedly having a penis. 63.5% of participants were between the ages of 21-39. 62% identified as white/caucasian and 20% identified as Asian. Slightly less than half of the respondents have been diagnosed with POIS. The most common symptoms experienced by undiagnosed people are mood disturbance/irritability (82.7%), extreme fatigue or exhaustion (82.7%), and concentration problems (77%). The most common symptom clusters experienced by diagnosed people are extreme fatigue, mood instability/irritability or depressed mood, muscle weakness, decreased cognition/concentration/word-finding ability (94%), headache, foggy feeling in the head, a heavy feeling in the head (68%), and muscle tension in the back or neck, muscle weakness, pain in muscles, heavy legs, stiffness (56%). Combined, 59% of participants have seen more than two physicians for their symptoms. 58% have a concurrent mental illness diagnosis and 29% have a digestive disease. Treatments trialed include NSAIDs, allergy medications, anti-depressants, testosterone, prednisone, alpha-blockers (i.e., silodosin), and niacin. Most treatment options resulted in respondents feeling the "same" or "somewhat better." 65% say this condition has "very negatively" affected their ability to enjoy sex or masturbation. CONCLUSIONS: Overall, POIS is a complicated sexual disorder that presents uniquely in every individual. However, several overlapping characteristics have been revealed including symptoms, comorbidities, impact on sexual enjoyment, and the lack of remarkable treatment options. This prospective registry will aid in future research and awareness, and hopefully help researchers determine more effective treatment options. Source of Funding: N/A © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e616 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Olivia Paulsen More articles by this author Ifeoma Ikedionwu More articles by this author Jasmin Banton More articles by this author John Sun More articles by this author Isaac Bronson More articles by this author Omer Raheem More articles by this author Amy M. Pearlman More articles by this author Mesut Berkan Duran More articles by this author Ege Can Serefoglu More articles by this author Rachel Rubin More articles by this author Expand All Advertisement PDF downloadLoading ...