Retrospective review demonstrates a 3.6% incidence of post-cystography infection in pediatric patients, suggesting pre-existing renal defects warrant targeted clinical management.
You have accessJournal of UrologyPediatrics IV (MP55)1 May 2024MP55-16 RISK OF UTI AFTER CYSTOGRAPHY IN a CONTEMPORARY PEDIATRIC POPULATION Peter Y. Cai, Tanya Logvinenko, Caitlynn Feng, Katelyn Ralston, Caleb P. Nelson, and Julia B. Finkelstein Peter Y. CaiPeter Y. Cai , Tanya LogvinenkoTanya Logvinenko , Caitlynn FengCaitlynn Feng , Katelyn RalstonKatelyn Ralston , Caleb P. NelsonCaleb P. Nelson , and Julia B. FinkelsteinJulia B. Finkelstein View All Author Informationhttps://doi.org/10.1097/01.JU.0001008616.01808.0f.16AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Voiding cystourethrogram (VCUG), radionuclide cystogram (RNC) and contrast-enhanced voiding urosonography (CEUS) are associated with post-cystography urinary tract infection (PCUTI). We sought to determine the incidence of and risk factors for PCUTI in a contemporary population of patients, in whom we had access to regional primary provider records. METHODS: A retrospective review of 1656 unique patients who underwent VCUG/RNC/CEUS at our institution (02/01/2021 – 08/15/2022) was performed. We excluded charts without access to regional primary provider records (n=681) and patients with at least 50,000 CFU/mL on urine culture from catheterization at time of cystography (n=60). PCUTI was defined as strict (fever+pyuria on urinalysis+at least 50,000 CFU/mL on urine culture) or pragmatic (included patients with high clinical suspicion for PCUTI prompting treatment) within 30 days of cystography. Clinical data were tabulated based on pragmatic definition of PCUTI and associations analyzed using chi-square and Fisher's exact test. RESULTS: Analysis included 913 patients with median age of 1.42 years (Table 1). Seventeen patients (1.9%) met strict definition for PCUTI and 33 (3.6%) met the pragmatic definition. Patient with PCUTI (pragmatic definition) were more likely to have parenchymal abnormalities on pre-cystography ultrasound (41.4% vs 22.4%, p=0.017) and have vesicoureteral reflux (VUR) but not be on continuous antibiotic prophylaxis (CAP) at the time of cystography (33.3% vs. 19.1%, p=0.035, Table 2). CONCLUSIONS: PCUTI occurs in 3.6% of patients within 30 days of undergoing cystography. Parenchymal abnormalities on prior ultrasound and having VUR but not being on CAP is associated with developing PCUTI. Identifying these risk factors will allow for improvement in our counseling and management of patients undergoing cystogram. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e922 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Peter Y. Cai More articles by this author Tanya Logvinenko More articles by this author Caitlynn Feng More articles by this author Katelyn Ralston More articles by this author Caleb P. Nelson More articles by this author Julia B. Finkelstein More articles by this author Expand All Advertisement PDF downloadLoading ...
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