Pd46-07 Long-Term Complications Free Survival and Risk Factors for Reintervention After Penile Prosthesis Implantation

You have accessJournal of UrologySexual Function/Dysfunction: Surgical Therapy I (PD46)1 May 2024PD46-07 LONG-TERM COMPLICATIONS FREE SURVIVAL AND RISK FACTORS FOR REINTERVENTION AFTER PENILE PROSTHESIS IMPLANTATION Skander Zouari, Lionel Mendel, Flora Barthe, Arnoult Morrone, Paula Lorena Charry Gonima, Romain Haider, Younes Ahallal, Matthieu Durand, Daniel Chevallier, and Imad Bentellis Skander ZouariSkander Zouari , Lionel MendelLionel Mendel , Flora BartheFlora Barthe , Arnoult MorroneArnoult Morrone , Paula Lorena Charry GonimaPaula Lorena Charry Gonima , Romain HaiderRomain Haider , Younes AhallalYounes Ahallal , Matthieu DurandMatthieu Durand , Daniel ChevallierDaniel Chevallier , and Imad BentellisImad Bentellis View All Author Informationhttps://doi.org/10.1097/01.JU.0001008900.49567.2e.07AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Penile prosthesis implantation (PPI) is the treatment for erectile dysfunction (ED) refractory to pharmacological therapies. Long-term data on factors associated with prosthesis survival remains unclear. Our aim was to analyze the long-term complications free survival of penile prostheses and identify risk factors associated with complications free survival. METHODS: This is a retrospective, single-center study of patients who underwent PPI between January 2014 and December 2022. Preoperative data related to the patient and the etiology of ED, as well as perioperative data, were collected. The primary outcome was complications free survival. Complications were defined as prosthesis revision or explantation due to mechanical dysfunction or infection. We conducted survival analyses without reintervention and searched for risk factors using a multivariate Cox model. RESULTS: In total, 36 out of 137 patients had complications leading to reintervention (26.3%), including 24 (17.5%) prosthesis revisions and 9 (6.6%) explantations. Main characteristics of the study population are summarized in Table 1. The median survival without reintervention was 7 years (Figure 1-A). In univariate analysis, only downsizing (p=0.048) was associated with reintervention (Figure 1-B). The median complications free survival with downsizing was shorter (42 versus 84 months, p=0.028). Smoking (p=0.003) and age (p=0.034) were associated with prosthesis explantation. Number of implantation (p=0.009) was associated with prosthesis revision. Multivariate analysis by Cox model did not identify any independent predictive factors for reintervention (Figure 1-C). CONCLUSIONS: Smoking was the only risk factor for infection. Primary implantations were associated with better survival. These results are in accordance with the literature. Adjusting cylinder size, known as downsizing, is likely to be a proxy for the complexity of the procedure and thus linked to earlier reintervention. Download PPT Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e976 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Skander Zouari More articles by this author Lionel Mendel More articles by this author Flora Barthe More articles by this author Arnoult Morrone More articles by this author Paula Lorena Charry Gonima More articles by this author Romain Haider More articles by this author Younes Ahallal More articles by this author Matthieu Durand More articles by this author Daniel Chevallier More articles by this author Imad Bentellis More articles by this author Expand All Advertisement PDF downloadLoading ...