Pd39-02 Focal Therapy Consensus: Recommendations of a Delphi Initiative to Consolidate Partial Gland Ablation in Localized Prostate Cancer

You have accessJournal of UrologyProstate Cancer: Localized: Ablative Therapy II (PD39)1 May 2024PD39-02 FOCAL THERAPY CONSENSUS: RECOMMENDATIONS OF A DELPHI INITIATIVE TO CONSOLIDATE PARTIAL GLAND ABLATION IN LOCALIZED PROSTATE CANCER Lara Rodriguez-Sanchez, Robert Reiter, Alejandro Rodriguez, Petr Macek, Pilar Laguna, Alberto Bossi, Eva Comperat, Luca Lunelli, Anita Mitra, George Schade, Georg Salomon, Peter Ka-Fung Chiu, Aiman Haider, Gaelle Fiard, José Luis Dominguez-Escrig, Bernardino Miñana, Marc Emberton, Phillip Stricker, Fernando Bianco, Anna Lantz, Theo de Reijke, Rafael Sanchez-Salas, and Falcon Consensus group Lara Rodriguez-SanchezLara Rodriguez-Sanchez , Robert ReiterRobert Reiter , Alejandro RodriguezAlejandro Rodriguez , Petr MacekPetr Macek , Pilar LagunaPilar Laguna , Alberto BossiAlberto Bossi , Eva ComperatEva Comperat , Luca LunelliLuca Lunelli , Anita MitraAnita Mitra , George SchadeGeorge Schade , Georg SalomonGeorg Salomon , Peter Ka-Fung ChiuPeter Ka-Fung Chiu , Aiman HaiderAiman Haider , Gaelle FiardGaelle Fiard , José Luis Dominguez-EscrigJosé Luis Dominguez-Escrig , Bernardino MiñanaBernardino Miñana , Marc EmbertonMarc Emberton , Phillip StrickerPhillip Stricker , Fernando BiancoFernando Bianco , Anna LantzAnna Lantz , Theo de ReijkeTheo de Reijke , Rafael Sanchez-SalasRafael Sanchez-Salas , and Falcon Consensus group View All Author Informationhttps://doi.org/10.1097/01.JU.0001008924.16121.42.02AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Focal Therapy (FT) for Prostate Cancer (PCa) has been accepted for evaluation under prospective registry assessment. Although improved functional outcomes are proven, long-term oncological results are awaited and there is no final consensus on the implementation of FT. Previously available consensus was limited to include experts' opinions on FT only. We aimed to conduct a consensus meeting, amongst a large group of PCa treatment physicians to propose a comprehensive approach for FT implementation. METHODS: A 154-item questionnaire was built following a stirring committee discussion and a literature search. From 2022 to 2023 the authors then performed three rounds of a Delphi Consensus (University of Liverpool, Comet Initiative Manager), using a 1-9 Likert scale with an "Unable to rate" option, followed by a face-to-face expert meeting. Six main areas of interest were covered including, 1) Patient selection, 2) Energy selection, 3) Treatment approach, 4) Treatment evaluation and follow-up, 5) Treatment cost and accessibility 6) Future perspectives. Respondents were invited to add new items during rounds 1 and 2. RESULTS: Out of the initial 254 participants; 148 (56%) completed the three Delphi rounds among the 181 statements considered in the second round (27 new statements); 33 questions related to personal expertise were excluded from subsequent rounds. After the third and final online round, 69 items did not reach a consensus. They were re-discussed, resulting in a consensus (n=57), and a consensus on uncertainty (n=12). A final list of statements was derived from the approved and discussed items, with the addition of generated statements, to provide guidance on FT. CONCLUSIONS: FALCON statements have provided an unprecedented comprehensive consensus guideline on implementing FT. Research efforts in FT could be guided by FALCON information. Source of Funding: The Falcon project has been supported by AngioDynamics © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e813 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Lara Rodriguez-Sanchez More articles by this author Robert Reiter More articles by this author Alejandro Rodriguez More articles by this author Petr Macek More articles by this author Pilar Laguna More articles by this author Alberto Bossi More articles by this author Eva Comperat More articles by this author Luca Lunelli More articles by this author Anita Mitra More articles by this author George Schade More articles by this author Georg Salomon More articles by this author Peter Ka-Fung Chiu More articles by this author Aiman Haider More articles by this author Gaelle Fiard More articles by this author José Luis Dominguez-Escrig More articles by this author Bernardino Miñana More articles by this author Marc Emberton More articles by this author Phillip Stricker More articles by this author Fernando Bianco More articles by this author Anna Lantz More articles by this author Theo de Reijke More articles by this author Rafael Sanchez-Salas More articles by this author Falcon Consensus group More articles by this author Expand All Advertisement PDF downloadLoading ...