May-Thurner Syndrome (MTS) occurs when the left common iliac vein is compressed by the anterior lying right common iliac artery leading to a lower extremity venous outflow obstruction. This outflow obstruction can progress to secondary venous hypertension, causing lower extremity swelling, discoloration, pelvic congestion, and venous ulcerations. The diagnosis of MTS is based on careful history, physical exam, and multiple imaging modalities such as duplex ultrasound, computed tomography/magnetic resonance venography, catheter-based venography, and intravascular ultrasound.
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Dunlap et al. (2024) studied this question.
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