Ugi Three-Component Coupling Strategy for the Synthesis of Bridged Bicyclic Iminosugars

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This is a Experimental Study study.

Goparaju Rakesh; Allam Vinaykumar; Dommati Soniya; Balasubramanian Sridhar; B. V. Subba Reddy

doi:10.1039/d5ob01246e

January 1, 2025Organic & Biomolecular Chemistry

Ugi Three-Component Coupling Strategy for the Synthesis of Bridged Bicyclic Iminosugars

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Key Points

A catalyst-free method efficiently synthesizes bridged bicyclic iminosugars under mild conditions using Ugi 3CC.
This synthesis utilizes tosylribose, primary amine, and isonitrile, demonstrating innovative use of materials in reactions.
The Ugi three-component coupling facilitates a straightforward assembly of complex structures without the need for catalysts.
These findings support the development of simpler synthetic routes in producing valuable organic compounds.

Implication

A novel approach synthesizes bridged bicyclic iminosugars using Ugi 3CC reactions, implying simplicity and efficiency.

Abstract

A novel and catalyst-free approach has been accomplished for the synthesis of bridged bicyclic iminosugars through a Ugi 3CC reaction of tosylribose, primary amine and isonitrile under mild conditions. This...

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Cite This Study

Rakesh et al. (2025) studied this question.

synapsesocial.com/papers/68e6f342f8145af55aeacb19 https://doi.org/10.1039/d5ob01246e

View Full Paper

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Ugi Three-Component Coupling Strategy for the Synthesis of Bridged Bicyclic Iminosugars

Key Points

Implication

Abstract

Discussion

Cite This Study

Ugi Three-Component Coupling Strategy for the Synthesis of Bridged Bicyclic Iminosugars

Key Points

Implication

Abstract

Discussion

Cite This Study

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