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October 8, 2025JCO Oncology Practice

Patients with rare cancers: Diagnosis and treatment patterns in the US.

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Authors

NYNova YangAJAhmedin JemalKYK. Robin Yabroff

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Overview

Descriptive analysis identifies distinct diagnosis and treatment patterns in patients with rare cancers, suggesting urgent interventions are needed.

Key Points

  • Patients diagnosed with rare cancers exhibit unique treatment challenges, as one-third did not receive treatment within 30 days of diagnosis.
  • Among 1,756,944 patients with rare cancers, 44.0% were treated at academic facilities, facing distinct diagnosis patterns and delays.
  • Early-stage diagnoses for rare cancers were notably less common compared to common cancers, with only 32.5% diagnosed at early stages.
  • Variability in treatment patterns exists; 24.3% of patients with early-stage rare cancers did not receive surgical treatment.

Cite This Study

Yang et al. (2025) studied this question.

synapsesocial.com/papers/68e6f342f8145af55aeaccbfhttps://doi.org/10.1200/op.2025.21.10_suppl.235
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prevalence of rare cancer survivors in the United States2025
  2. 2Prevalence of rare cancer survivors in the United States2025
  3. 3Cancer rarity and mortality: Evidence from a nationwide cohort study2026
  4. 4Clinical benefits of early-phase clinical trials for rare malignancies: Asian single-center analysis.2026
  5. 5SURGICAL MANAGEMENT OF RARE TUMORS (Part 1)2024