October 8, 2025JCO Oncology Practice

Treatment delays and risk of metastatic progression in colorectal cancer patients undergoing curative surgery: Real-world evidence from a national claims database.

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Delays in treatment initiation increase the risk of metastatic relapse in colorectal cancer patients.
In a cohort of 11,927 patients, an 18% higher risk of relapse was identified for delays of 4-20 days post-diagnosis.
Treatment delay intervals were determined using machine learning methods, highlighting varied responses in relapse risk.
Timely initiation of treatment could inform oncologists in decision-making to improve patient outcomes.

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Implication

Retrospective cohort study links treatment delay to increased metastatic relapse risk in non-metastatic colorectal cancer patients, suggesting critical implications for care.

Cite This Study

Nguyen et al. (2025) studied this question.

synapsesocial.com/papers/68e6f342f8145af55aeacce2 https://doi.org/10.1200/op.2025.21.10_suppl.453

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Implication

Retrospective cohort study links treatment delay to increased metastatic relapse risk in non-metastatic colorectal cancer patients, suggesting critical implications for care.

Treatment delays and risk of metastatic progression in colorectal cancer patients undergoing curative surgery: Real-world evidence from a national claims database.

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Implication

Cite This Study

Treatment delays and risk of metastatic progression in colorectal cancer patients undergoing curative surgery: Real-world evidence from a national claims database.

Key Points

Discussion

Implication

Cite This Study

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