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October 8, 2025JCO Oncology Practice

Racial disparities in clinical trial enrollment among patients with advanced cancers in community practices.

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Authors

CLChangzheng LuSouthwestern Medical Center XHXin HuAmerican Cancer Society SZSong ZhangThe University of Texas Southwestern Medical Center

Discussion

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Implication

Retrospective analysis of clinical trial enrollment reveals significant racial disparities among patients, suggesting urgent need for equitable access.

Key Points

Racial disparities in clinical trial enrollment among patients with advanced cancers persist, affecting access to innovative treatments.
Among 205,743 patients, only 5.3% received clinical study drugs, with enrollment rates varying significantly across racial groups.
This retrospective analysis utilized the Flatiron Health Research Database to assess trends and disparities from 2010 to 2024.
Addressing these disparities is critical for ensuring equitable access to advanced cancer therapies in community oncology settings.

Cite This Study

Lu et al. (2025) studied this question.

synapsesocial.com/papers/68e6f342f8145af55aeaccf0 https://doi.org/10.1200/op.2025.21.10_suppl.124

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Implication

Retrospective analysis of clinical trial enrollment reveals significant racial disparities among patients, suggesting urgent need for equitable access.

Racial disparities in clinical trial enrollment among patients with advanced cancers in community practices.

Discussion

Member takes

Implication

Key Points

Cite This Study

Racial disparities in clinical trial enrollment among patients with advanced cancers in community practices.

Discussion

Member takes

Implication

Key Points

Cite This Study

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