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October 8, 2025JCO Oncology Practice

Enhancing cancer risk identification through a digital genetic risk assessment tool.

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Authors

FPFernanda PolubriaginofMemorial Sloan Kettering Cancer CenterMSMargaret SheehanMemorial Sloan Kettering Cancer CenterGDGrisselle DeFrank

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Overview

Retrospective analysis evaluates the genetic risk assessment tool's impact on clinic workflow, indicating improved efficiency.

Key Points

  • The GRA tool effectively identifies high-risk individuals for genetic testing, improving clinic efficiency with 31% of DTT patients post-Epic.
  • A retrospective analysis from July 2021 to March 2025 showed a significant reduction in unnecessary appointments for genetic counseling.
  • MSK's GRA tool automates genetic risk assessment through a questionnaire and algorithm aligned with NCCN guidelines.
  • The successful integration of the GRA tool into Epic underscores its potential for widespread adoption in genetic testing practices.

Cite This Study

Polubriaginof et al. (2025) studied this question.

synapsesocial.com/papers/68e6f342f8145af55aeacd17https://doi.org/10.1200/op.2025.21.10_suppl.456
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A randomized controlled trial of a multilingual digital genetic cancer risk assessment tool in a diverse patient population.2026
  2. 2A personalized digital approach to cancer risk assessment in a diverse gynecology clinic.2026
  3. 3Developing the MyCancerGene Digital Health Portal to Improve Patients’ Understanding of Germline Cancer Genetic Test Results: Development, User, and Usability Testing Study2024 · 1 citations
  4. 4Improving feasibility and timeliness of hereditary cancer risk assessment with a brief patient-administered digital tool and rapidly available telehealth genetic counseling.2024 · 1 citations
  5. 5Streamlining Inherited Cancer Identification via an EMR-Integrated Risk Assessment Platform2026