Serial Evaluation of Sofa Score for Predicting Outcome in Critically Ill Patients Admitted in Medical Icu

Sepsis is a life threatening organ dysfunction caused by dysregulated host response to infection. The incidence of sepsis related mortality is 85% in Indian ICU. The Sequential Organ Failure Assessment (SOFA) score is a simple and objective score in patients of sepsis admitted in ICU. The aim of this study was to determine the usefulness of Serial SOFA Score and DELTA SOFA Score for prediction of the outcome in patients with severe sepsis admitted in Medical ICU. SOFA Score on admission to ICU, at 48 hours, at 96 hours and DELTA SOFA Score were calculated. Study showed that increase in Serial SOFA Score of 12 and above at 48 hour is associated with high mortality (92.85% mortality). The Serial SOFA Score of 12 and above at 96 hours is associated with a 95.23% mortality. SOFA score at 48 hours and 96 hours as well as DELTA SOFA score are useful predictors of outcome as compared to SOFA score at admission. In this study, SOFA 48 hours, 96 hours, DELTA SOFA showed mortality with P value <0.001 which is statistically signicant. Hence use of Serial SOFA score and DELTA SOFA score are good predictors of outcome in patients of sepsis.