Comparative analysis observes EBV DNA frequency across cerebrospinal fluid and blood in multiple sclerosis, highlighting the compartmental distribution of infected B cells.
Epstein-Barr virus (EBV) infection is a major risk factor of multiple sclerosis (MS). We examined the presence of EBV DNA in the CSF and blood of patients with MS and controls. We analyzed whether EBV DNA is more common in the CSF of patients with MS than in controls and estimated the proportions of EBV-positive B cells in the CSF and blood.
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Lehikoinen et al. (2024) studied this question.
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