Abstract Exposure to endocrine disrupting chemicals (EDCs) can result in alterations of natural hormones in the body. The aim of this review article is to gather current knowledge about EDCs and obesity in humans. We conducted an electronic literature search using PubMed platform for studies published between y. 2013-2023 on EDCs and obesity. A total of 12 studies met our inclusion criteria focusing on more prominent EDCs such as bisphenols, parabens, triclosan, and phthalates, and their association with obesity. A few experimental studies have been performed on association of obesity and EDCs in humans. Obesity was mostly related to EDCs such as bisphenols and phthalates, while less is known about the impact of parabens and triclosan. Series of negative physiological effects involving obesogenic, diabetogenic, and inflammatory mechanisms, epigenetic and microbiota modulations were related to prolonged EDCs exposure. More profound research of obesity with specific design regarding its role, genetic background for diabetes-related features, cardiometabolic risks and anthropometrical exceeds are needed to illuminate the effect of EDCs exposure on human populations in different environments.
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Amon et al. (2024) studied this question.
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