Answers are grounded in this paper and cite their sources.
Matching-adjusted indirect comparison reports three-year treatment effects of troriluzole in spinocerebellar ataxia, suggesting a framework to evaluate therapy against natural progression.
To understand the treatment effect of troriluzole over 3 years in patients with spinocerebellar ataxia (SCA) by conducting a matching-adjusted indirect comparison (MAIC) of troriluzole-treated subjects vs subjects in a pooled natural history cohort.
No takes yet. Share an insight, caveat, or question.
Beiner et al. (2024) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: