Real-time quaking induced conversion (RT-QUIC) test is ~92% sensitive and ~98% specific for Creutzfeldt Jakob disease (CJD). True negatives occur in rapidly progressive, familial or younger cases. False negatives are rare. Through this sporadic case with initially negative RT-QUIC, we highlight the importance of repeat interval testing in cases with strong clinical suspicion.
No takes yet. Share an insight, caveat, or question.
Vijaywargiya et al. (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: