In this study, we utilized a seed amplification assay called real-time quaking inducing conversion (RT-QuIC) to determine whether aggregation-prone α-synuclein (α-syn) is present and detectable in submandibular and esophageal tissue of patients with synucleinopathies and whether the kinetics of aggregation differ for these two conditions.
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Yamasaki et al. (2024) studied this question.
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