We explored the association of cardiovascular risk factors with CSF markers of amyloid deposition and neurodegeneration stratifying patients with Alzheimer's Disease (AD) according to age-of-onset: early (< 65, EOAD), classic (65–75, COAD), late (>75, LOAD). Then, we evaluated the effects of vascular comorbidities on cognitive decline and their interplay with albumin quotient (Qalb), accounting for blood-brain-barrier (BBB) integrity, and neurodegeneration.
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Bonomi et al. (2024) studied this question.
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