Coarse-scale Optoretinography (CoORG) is an ORG approach that enables quick (10min), extended-field (5 deg) assessment of retinal structure and function. This study explores the feasibility of CoORG in discerning early and sensitive changes in retinitis pigmentosa (RP). In general, diminished cone function is observed in RP compared to normals using CoORG, even in areas of normal apparent outer retinal structure. This underscores the potential of CoORG for early & sensitive detection of retinal dysfunction in diseases such as RP and AMD.
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Liu et al. (2024) studied this question.
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