We review in this paper the hallmarks of cancer (described by Hanahan and Weinberg) from genomic perspective and we give examples of genomic alterations underlying each of the 10 biological characteristics. We explore examples of current FDA approved therapies that target specific pathways belonging to the different hallmarks of cancer. We also propose an addition to the 10 hallmarks of cancer.
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Dib et al. (2024) studied this question.
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