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April 5, 2024Journal of the National Comprehensive Cancer Network

CRE24-035: Pembrolizumab-Induced Hemophagocytic Lymphohistiocytosis in a Patient With Breast Cancer: A Case Report and Systematic Review of the Literature

Charlotte S. Walmsley Michael Andersen Barbara D. Lam Deepa Rangachari Shana Berwick Rushad Patell

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Abstract

"CRE24-035: Pembrolizumab-Induced Hemophagocytic Lymphohistiocytosis in a Patient With Breast Cancer: A Case Report and Systematic Review of the Literature" published on 05 Apr 2024 by National Comprehensive Cancer Network.

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Walmsley et al. (2024) studied this question.

synapsesocial.com/papers/68e70542b6db64358767ebbb https://doi.org/10.6004/jnccn.2023.7307

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Hemophagocytic lymphohistiocytosis/cytokine release syndrome secondary to neoadjuvant pembrolizumab for triple-negative breast cancer: a case study2024 · 8 citations
2Pembrolizumab-Associated Hemophagocytic Lymphohistiocytosis in Clear Cell Renal Carcinoma: Case Report and Literature Review2025 · 2 citations
3No Germs, Just Cytokines: A Case of Immunotherapy-Induced Hemophagocytic Lymphohistiocytosis Masquerading as Neutropenic Sepsis in a Patient With Inflammatory Breast CancerOriginal Research · 2026
4Pembrolizumab-associated hemophagocytic lymphohistiocytosis in recurrent metastatic squamous cell carcinoma of the ovary arising in a teratomaReview · 2026 · 1 citations
5PS5-06-20: Autoimmune Hemolytic Anemia Triggered by Neoadjuvant Pembrolizumab in Triple Negative Breast Cancer: A Case ReportCase Report · 2026

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Haemophagocytic Lymphohistiocytosis Following Ipilimumab and Nivolumab in Malignant Pleural Mesothelioma: A Case Report2026
Clinical Features, Treatment, and Outcomes of Nivolumab-Induced Hemophagocytic Lymphohistiocytosis2024
Unchecked Immunity to Unleashed Anarchy: A Case of Hemophagocytic Lymphohistiocytosis Following Combination Immune Checkpoint Inhibitor Therapy2025

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