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April 3, 2024International Journal of Molecular SciencesOpen Access

Water Extracts from Industrial Hemp Waste Inhibit the Adhesion and Development of Candida Biofilm and Showed Antioxidant Activity on HT-29 Colon Cancer Cells

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Authors

LDLeonardo DonatiDPDebora Casagrande PierantoniACAngela Conti

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Overview

In vitro study shows hemp waste extracts inhibit Candida biofilms and oxidative stress in HT-29 colon cancer cells, highlighting sustainable biomedical uses for agricultural waste.

Key Points

  • Water extracts from industrial hemp waste suppress the adhesion and development of Candida biofilms, while providing protective antioxidant activity against cellular oxidative stress.
  • All 5 water extracts demonstrated antimicrobial efficacy against both planktonic and sessile cells of Candida albicans, Candida parapsilosis, and Candida tropicalis strains.
  • Preclinical cell testing highlights the therapeutic potential of valorizing industrial Cannabis sativa waste, though further in vivo research is required; cell culture limits apply.

Cite This Study

Donati et al. (2024) studied this question.

synapsesocial.com/papers/68e708c9b6db6435876823cdhttps://doi.org/10.3390/ijms25073979
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Attempts to Use Hemp (Cannabis sativa L. var. sativa) Inflorescence Extract to Limit the Growth of Fungi Occurring in Agricultural Crops2024 · 8 citations
  2. 2Spent Material Extractives from Hemp Hydrodistillation as an Underexplored Source of Antimicrobial Cannabinoids2024 · 5 citations
  3. 3The Potential of Hemp Extracts to Modify the Course of Oxidative-Stress Related Conditions2024 · 6 citations
  4. 4Exploring (Un)Covered Potentials of Industrial Hemp (<i>Cannabis sativa</i> L.) Essential Oil and Hydrolate: From Chemical Characterization to Biological Activities2024
  5. 5Antimicrobial, Probiotic, and Immunomodulatory Potential of Cannabis sativa Extract and Delivery Systems2024 · 6 citations