Supplementary Figure 5 from Tumor Burden Dictates the Neoantigen Features Required to Generate an Effective Cancer Vaccine

Representative numbers of total and #23+ CD8+ T cells in tumor and spleen of Help versus non Help vaccine. A) Experimental scheme, FACS gating strategy with representative FACS plots of intratumoral #23+ CD8+ T cells in Help group and untreated group. B and C) Average number of total CD8+ and #23+ T cells relative to figure 6B, 6C, 6E, 6F, per each experimental group (Untreated, Help and No Help) in tumor (B) and in spleen (C) at day 14 post immunization. Number (n) of total CD8+ (x104 cells) and Ag-#23+ specific (x102 cells). Data are shown as total cell count per tumor / organ.