Figure S2 from Mass Spectrometry–Based Proteomics Identifies Serpin B9 as a Key Protein in Promoting Bone Metastases in Lung Cancer

SB9 expression is associated with lung cancer bone metastasis A. Kaplan-Meier curves with a survival period of 28 to 3650 days for overall survival analysis of the LUSC(Lung squamous cell carcinoma) patients from TCGA(The Cancer Genome Atlas Program). The red line represents the high expression group, and the blue line denotes the low expression group. Only these genes with a P value < 0.05 were considered as prognostic-related genes. B. Functional enrichment analysis of differential proteins. Top ten biological functions closely related to differential proteins in GO analysis. C-D. Secondary mass spectrogram of two specific peptides of SB9 protein. E. The standard curve of ELISA assay to measure the SB9 protein in condition-media of LLC1-BM3 and LLC1-Pa.