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October 7, 2025

Table S4 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia

Haley Newman Shawn H.R. Lee Petri Pölönen Rawan Shraim Yimei Li Hongyan Liu Richard Aplenc Shovik Bandyopadhyay Changya Chen Meenakshi Devidas Caroline Diorio Kimberly P. Dunsmore Omar Elghawy Amira Elhachimi Thomas Fuller Sumit Gupta Junior Hall Andrew D. Hughes Stephen P. Hunger Mignon L. Loh Zachary Martinez Michael F. McCoy Cassidy G. Mullen Stanley Pounds Elizabeth A. Raetz Anna Eames Seffernick Gongping Shi Jonathan Sussman Kai Tan Lahari Uppuluri Tiffaney L. Vincent Ruth Wang’ondu Lena E. Winestone Stuart S. Winter Brent L. Wood Gang Wu Jason Xu Wenjian Yang Charles G. Mullighan Jun J. Yang Kira Bona David T. Teachey

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Key Points

Genetic ancestry impacts survival outcomes in patients with T-cell acute lymphoblastic leukemia, enhancing treatment strategies.
Pathway alterations linked to genetic ancestry were identified, potentially guiding personalized therapy approaches.
This research utilized genetic data to explore implications for survival and treatment in diverse patient populations.
Findings suggest the need for further studies to validate these relationships across different genetic backgrounds.

Implication

Analysis shows genetic ancestry influences survival outcomes in T-cell acute lymphoblastic leukemia, indicating key pathway alterations.

Abstract

T-cell Acute Lymphoblastic Leukemia Pathway Alterations by Categorical Genetic Ancestry

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Cite This Study

Newman et al. (2025) studied this question.

synapsesocial.com/papers/68e70dab90569dd607ee5f5b https://doi.org/10.1158/2643-3230.30296491

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Table S4 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia2025
2Table S2 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia2025
3Table S5 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia2025
4Table S5 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia2025
5Table S6 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia2025