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October 9, 2025Journal of Circulating Biomarkers4 citationsOpen Access

Association of hypertension and diabetes with COVID-19 severity in comparison to healthy patients

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MAMohammed Hadi Ali Al‐JumailiMIMohammad IsmailAHAbdelaziz M. Hussein

Key Points

  • Patients with diabetes and hypertension admitted to ICU showed greater COVID-19 severity.
  • The study found a 33% ICU admission rate among diabetic and hypertensive patients compared to healthy individuals.
  • Clinical evaluations indicated higher mortality rates in diabetic COVID-19 patients, emphasizing critical comorbidities.
  • Data for 150 patients were analyzed, highlighting differences in outcomes among diabetic and non-diabetic individuals.

Abstract

Introduction: The coronavirus is a novel pandemic disease that began in Wuhan, China, and further spread globally. Therefore, the aim of this retrospective work was to look at the clinical characteristics and outcomes ofdiabetic and blood pressure patients compared with a healthy patient who was infected with coronavirus disease(COVID-19).Methods: Data and outcomes were gathered from medical records and analyzed in 150 patients. The disease isfrequently diagnosed via nucleic acid-based viral identification from swabs, sputum, or bronchial alveolar lavagefluid (BALF) using diagnostic reagents such as quantitative reverse transcription-polymerase chain reaction(RT-qPCR). COVID-19 chest radiographs were obtained, and clinical characteristics and outcomes were evaluated.In this study, we analyzed and compared the severity of the disease, its outcome, any associated complications,and clinical laboratory findings in COVID-19 patients between diabetic, hypertensive, and healthy individuals.Results and Conclusion: According to the findings, COVID-19 can cause a wide range of symptoms, which rangefrom asymptomatic to severe respiratory problems and death. Diabetes appears to be one of the most significantcomorbidities associated with a worse COVID-19 result. COVID-19 patients with diabetes (50 (33%) and hypertension (50 (33%)) had more ICU admissions compared with the non-diabetic and non-blood pressure patients (50 (33%)). During the treatment follow-up, 10 (6.6%) of the 150 patients passed away, 140 (93%) were released, 110 (73%) were discharged, and 30 (20%) kept in the hospital. Compared to non-diabetic and healthy COVID-19 patients, diabetic COVID-19 patients had a greater mortality rate.

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Cite This Study

Al‐Jumaili et al. (2025) studied this question.

synapsesocial.com/papers/68e70dab90569dd607ee5f60https://doi.org/10.33393/jcb.2025.3561
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