April 1, 2024Open Access

APAF1 Silencing Ameliorates Diabetic Retinopathy by Suppressing Inflammation, Oxidative Stress, and Caspase-3/GSDME-Dependent Pyroptosis

YDYuanyuan DingXi'an University of Science and Technology LCLinjiang ChenUniversity of Science and Technology of China JXJing XuArmy Medical University

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Abstract

Diabetic retinopathy (DR) can cause permanent blindness with unstated pathogenesis. We aim to find novel biomarkers and explore the mechanism of apoptotic protease activating factor 1 (APAF1) in DR.

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