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Current review highlights the incidence and pathophysiology of diabetic nephropathy, suggesting implications for renal replacement therapy.
Diabetic nephropathy (DN) is the leading cause of chronic kidney disease (CKD) and its progression to end stage renal disease (ESRD) worldwide, necessitating renal replacement therapy (RRT) in the form of dialysis or transplant. Proteinuria had been the hall mark of diabetic nephropathy until recently, reduced glomerular filtration rate without proteinuria has been frequently observed and labelled as non-proteinuric diabetic nephropathy. The current review discusses the incidence and possible pathophysiology and associated issue with this entity.
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Muhammad Mubeen Anwar (2021) studied this question.
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