WCN24-2479 Minocycline-induced Drug sensitivity syndrome with eosinophilia and systemic symptoms (Dress) with development of severe acute interstitial nephritis

DRESS is a severe hypersensitivity reaction to drugs, characterized by rash, fever, lymphadenopathy, systemic involvement and hematological alterations.The most frequently affected organs are skin, liver, lung, kidney, heart and central nervous system. It develops 2-6 weeks after initiation of the responsible medication. It has been described in association with multiple drugs, the most frequently involved being aromatic anticonvulsants and sulfonamides.We report the case of a 13year-old girl with DRESS syndrome induced by minocycline.