Prospective observational study of a novel self-assembling peptide hemostatic gel for initial hemostasis in endoscopic sphincterotomy-related hemorrhage

Aims Bleeding is recognized as one of the most commonly encountered adverse events associated with endoscopic sphincterotomy (EST). Although various techniques for endoscopic hemostasis have been reported, the treatment choice is left to the endoscopist. A novel self-assembling and fully synthetic hydrogel peptide (hemostatic gel) is currently developed as a hemostatic agent. This study aimed to evaluate the feasibility and effectiveness of the application of hemostatic gel to EST-related hemorrhage.