Endoscopic ultrasound guided biopsy of focal liver lesions: a tertiary care single center experience

Methods All consecutive patients who underwent EUS-FNB of a focal liver lesion between 2003 and 2023 were retrospectively analyzed. All procedures were performed with patients under deep sedation. Efficacy was evaluated considering technical success, adequacy and accuracy of histological diagnosis. Adequacy was defined as the ability of the technique to confer a histological diagnosis. Accuracy was define as the agreement between definitive histology after surgery (for resectable patients), radiologic findings or clinical course during follow-up. "Malignant" was defined as a case with histologically malignant findings", and "benign" cases were those with "histologically benign findings on EUS-FNB and no tumor growth even after one-year follow-up". Sensitivity and specificity were also evaluated. Adverse events were defined according to American Society of Gastrointestinal Endosocopy (ASGE) lexicon.