Continuous Renal Replacement Therapy (CRRT) Protocol in Critically Ill Children

Definition of Continuous Renal Replacement Therapies and Methods UsedContinuous renal replacement therapies are extracorporeal support systems in which solute and/or water clearance is achieved in the time desired by the clinician using dialysis (diffusion-based solute removal) and/or filtration (convectionbased water and solute removal) methods. 3Terminology 1. Route; vascular access is necessary for blood flow to reach the extracorporeal system Venovenous route -This is a vascular access method that does not require arterial access.Two separate catheters are placed in two veins or a double-lumen catheter in a single vein.Blood is directed to the extracorporeal system using a pump.Advantage -No arterial intervention is required.Fast and predictable blood flow is provided.Disadvantage -A pump is required to access the extracorporeal system.Air embolism, thrombosis, or stenosis of the venous system may develop.