Oxidative stress plays a central role in atherogenesis, a common chronic inflammatory disease in patients with chronic kidney disease (CKD), characterised by the accumulation of fatty substances into the vascular subintimal layer, mainly the modified LDL under the presence of reactive oxygen species (ROS) forming oxidised LDL (oxLDL), which participates in the development of atherosclerosis along with inflammation. Nutritional strategies have been proposed as an adjuvant therapeutic to modulate oxidative stress based on the role of bioactive compounds on scavenger ROS.
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Fonseca et al. (2024) studied this question.
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