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March 1, 2004Journal of the American Society of Nephrology

The Role of Oxidative Stress–Altered Lipoprotein Structure and Function and Microinflammation on Cardiovascular Risk in Patients with Minor Renal Dysfunction

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Population

Patients with minor renal dysfunction / early stages of chronic kidney disease

Design

Review

Authors

GKGeorge A. KaysenJEJason P. Eiserich

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Overview

May inform CV risk assessment in mild CKD but should not change practice; leaves open whether targeting these pathways improves outcomes.

Structured PICO

P
Population
Patients with minor renal dysfunction / early stages of chronic kidney disease

Minor renal dysfunction contributes to cardiovascular risk through oxidative stress, altered lipoprotein structure and function, and microinflammation.

Cite This Study

Kaysen et al. (2004) studied this question.

synapsesocial.com/papers/6a70559c6ceb2bbd16dfdc1fhttps://doi.org/10.1097/01.asn.0000111744.00916.e6
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Endothelial dysfunction in chronic renal failure: roles of lipoprotein oxidation and pro‐inflammatory cytokines2001 · 289 citations
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  3. 3Pathophysiology Underlying Accelerated Atherogenesis in Renal Disease2004 · 53 citations
  4. 4Could Antioxidant Supplementation Delay Progression of Cardiovascular Disease in End-Stage Renal Disease Patients?2020 · 19 citations
  5. 5Increased cardiovascular risk in patients with chronic kidney disease2024 · 49 citations