Why the study?
What is the relationship between CRP, endothelial function, and oxidative stress markers in patients with CKD stage 3-5?
Population
44 consecutive patients with chronic kidney disease (CKD) K/DOQI stage 3-5
Design
Cross-sectional
Key result
In patients with CKD stage 3-5, CRP was related to lipid peroxidation, while endothelial function was related to intracellular oxidative stress, with no correlation between CRP and endothelial function.
Authors
Loading...
May link inflammation, endothelial dysfunction, and oxidative stress in CKD stages 3-5; leaves open causal prognostic role.
Cross-Sectional (n=44)
What is the relationship between CRP, endothelial function, and oxidative stress markers in patients with CKD stage 3-5?
In patients with CKD, CRP and endothelial function are associated with different pathways of oxidative stress and are unrelated to each other, suggesting they may provide complementary prognostic information for cardiovascular risk.
Annuk et al. (2005) conducted a cross-sectional in Chronic kidney disease (n=44). CRP and endothelium dependent vasodilation (EDV) was evaluated on Relationship between CRP, EDV, and oxidative stress markers. In patients with CKD stage 3-5, CRP was related to lipid peroxidation, while endothelial function was related to intracellular oxidative stress, with no correlation between CRP and endothelial function.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: