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Podocyte injury is a key event in glomerular disease (GD) pathogenesis. Urinary biomarkers specific for podocyte injury could aid in the diagnosis and surveillance of GD activity. In this study, we assessed three candidate biomarkers of podocytopathy – podocalyxin, podocin, and nephrin – and their associations with eGFR, proteinuria, underlying histopathologic changes, and foot process effacement (FPE) in GD.
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Schmidt et al. (2024) studied this question.
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