Renal impairment significantly affects the morbidity and death rates of cirrhosis patients. The estimated glomerular filtration rate (eGFR) calculation techniques and equations are derived from studies that did not include cirrhosis patients. These equations are erroneous and unreliable due to sarcopenia in cirrhosis. Further, the precision of eGFR equations varies across different ethnic groups. Cystatin C (CysC) based eGFR is more reliable as compare to Creatinine based eGFR in cirrhotic patients as Cystatin C is unrelated to muscle volume and liver function but have fallacies in presence of cirrhosis.
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Divyaveer et al. (2024) studied this question.
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