Infection-related glomerulonephritis (IRGN) is an immune complex-mediated acute glomerulonephritis that involves both in situ and circulating immune complexes associated with many non-renal infections with heterogeneous set of infectious foci. There has been a paradigm shift in the epidemiology of IRGN over the decades. From being a disease involving children with a good prognosis, it is now increasingly seen in adults where the majority of patients progress to CKD and ESRD. Studies from the Indian Subcontinent are few and retrospective in nature.
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G et al. (2024) studied this question.
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