WCN24-1644 CONSEQUENCES of EXPOSURE to FAMINE EXPOSURE on the eGFR DECLINE and LATER LIFE CKD RISK AMONG SURVIVORS of the GREAT CHINESE FAMINE: a RETROSPECTIVE STUDY

Chronic kidney disease (CKD) is an increasing contributor to the socio-economic burdendisease burden in China and globally. Previous findings indicated that the experience of exposure to childhood famine is associated with various chronic illnesses diseases such as diabetes, hypertension high blood pressure, and proteinuriaurinary protein levels. However, no clear conclusions were drawn about the long term consequences of human early life famine exposure on adulthood kidney function. In this study, we aimed to explore whether exposure to the Chinese Great Famine (from 1959 to 1962) was associated with the later life glomerular filtration rate (GFR) decline and the CKD risk.