Focal segmental glomerulosclerosis (FSGS) is the most frequent primary glomerulopathy in México and the one that most frequently progresses to chronic kidney disease, with a 10-year global renal survival of 50%. Therefore, it is important to identify the factors that predict the progression of renal disease. The first line of treatment recommended in the KDIGO guidelines is prednisone with which partial remission + complete remission of proteinuria is achieved in 50-64% of patients. However, little is known about the significance of the initial response to prednisone in the progression of renal disease.
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Sánchez et al. (2024) studied this question.
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