Smaller Gold Nanoparticles Release DNA More Efficiently During fs Laser Pulsed Optical Heating (Small 14/2024)

Gold nanoparticles, AuNPs, produce short-lived localized heat gradients under pulsed laser irradiation.Though only extending tens of nm and lasting a few ns, these heat gradients activate nucleotide release.Contrary to theoretical predictions that larger AuNPs, 55 nm diameters, would produce the fastest DNA release, smaller AuNP diameters (25 nm) led to faster dsDNA denaturation rates.More in article number 2303136, Sebastián A. Díaz and co-workers.