The authors report a rare case of successfully treated endogenous endophthalmitis in an 11-year-old healthy child who presented with a sudden decrease in vision associated with redness and pain in his left eye. There was no history of ocular trauma or recent hospitalization. The patient had acute severe panuveal inflammation with white hypopyon. Emergency pars plana vitrectomy with lensectomy was done and intravitreal antibiotics were administered. Vitreous biopsy grew Serratia marcescens on blood agar. The patient was treated with multiple intravenous, oral, and topical antibiotics based on VITEK 2 antibiotic susceptibility testing. Secondary intraocular lens implantation resulted in a best corrected visual acuity of 20/60.
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