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April 1, 2024Croatian Medical JournalOpen Access

The effect of somatic mutations in mitochondrial DNA on the survival of patients with primary brain tumors

Siti Zulaikha Nashwa Mohd Khair Siti Muslihah Ab Radzak Zamzuri Idris Anani Aila Mat Zin Wan Muhamad Amir W Ahmad Abdul Aziz Mohamed Yusoff

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Abstract

To assess the presence of mitochondrial (mt) DNA somatic mutations, determine the relationship between clinicopathological characteristics and mutations, and assess the survival outcomes in Malay patients with primary brain tumors.

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Cite This Study

Khair et al. (2024) studied this question.

synapsesocial.com/papers/68e71615b6db64358768f19a https://doi.org/10.3325/cmj.2024.65.111

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Mitochondrial Deoxyribonucleic Acid Copy Number Elevation As a Predictor for Extended Survival and Favorable Outcomes in High-Grade Brain Tumor Patients: A Malaysian Study2024 · 3 citations
2Mitochondrial DNA Changes in Genes of Respiratory Complexes III, IV and V Could Be Related to Brain Tumours in HumansOriginal Research · 2022 · 10 citations
3Somatic Mutations in Nuclear and Mitochondrial Genes of Mitochondrial Proteins in Primary and Recurrent GlioblastomaOriginal Research · 2026 · 1 citations
4The mitochondrial apoptosis profile in meningiomas and gliomas: Comparing the effects of patient sex, tumor histology, and grade.Original Research · 2026
5A mutational process signature and genomic alterations associated with outcome and immunogenicity in cancers with brain metastasis2025

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