Achalasia and hyperthyroidism: A co-occurrence revealing autoimmune connections

Achalasia is a rare esophageal motility disorder characterized by an unknown etiology, myenteric inflammation, and autoimmune markers. We present a case of a 43-year-old female with progressive dysphagia, regurgitation, generalized weakness, and hair loss. Despite normal cranial nerves and normal laboratory values, upper GI endoscopy revealed pangastritis, while manometry indicated type 2 achalasia cardia. The patient underwent laparoscopic Heller's myotomy for achalasia and received treatment for hyperthyroidism. The discussion explores the autoimmune aspects of achalasia and its rare association with hyperthyroidism. Early diagnosis and management are crucial for improving patient outcomes.