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This is a Literature Review study.

Achalasia and Thyroid Disorders: A Hidden Autoimmune Overlap? Epidemiology, Mechanisms, and Clinical Relevance of an Emerging Association

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Thyroid disorders are more common in achalasia, indicating a possible autoimmune connection.
Evidence shows up to 25% of achalasia cases may have thyroid dysfunction, with a threefold risk of autoimmune thyroid disease.
Multicenter data reveals thyroid autoimmunity in 20% of achalasia patients, suggesting a shared pathogenesis.
Early identification of thyroid issues may enhance management of achalasia, with further studies needed for causality.

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Narrative review reports higher thyroid disorders prevalence in achalasia patients, suggesting an autoimmune link.

Fernicola et al. (2025) studied this question.

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